ENSG00000171130


Homo sapiens

Features
Gene ID: ENSG00000171130
  
Biological name :ATP6V0E2
  
Synonyms : ATP6V0E2 / ATPase H+ transporting V0 subunit e2 / Q8NHE4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q36.1
Gene start: 149872968
Gene end: 149880698
  
Corresponding Affymetrix probe sets: 213587_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475904
Ensembl peptide - ENSP00000482231
Ensembl peptide - ENSP00000481176
Ensembl peptide - ENSP00000396148
Ensembl peptide - ENSP00000410220
Ensembl peptide - ENSP00000411672
Ensembl peptide - ENSP00000417939
Ensembl peptide - ENSP00000420012
Ensembl peptide - ENSP00000420679
Ensembl peptide - ENSP00000475645
NCBI entrez gene - 155066     See in Manteia.
OMIM - 611019
RefSeq - NM_001100592
RefSeq - NM_001289990
RefSeq - NM_145230
RefSeq Peptide - NP_001094062
RefSeq Peptide - NP_660265
RefSeq Peptide - NP_001276919
swissprot - Q8NHE4
swissprot - F8WDM2
swissprot - E9PAS2
Ensembl - ENSG00000171130
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atpv0e2ENSDARG00000059057Danio rerio
 ATP6V0E2ENSGALG00000020754Gallus gallus
 Q91XE7ENSMUSG00000039347Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15342 / ATP6V0E1 / ATPase H+ transporting V0 subunit e1ENSG0000011373217


Protein motifs (from Interpro)
Interpro ID Name
 IPR008389  ATPase, V0 complex, subunit e1/e2
 IPR017385  ATPase, V0 complex, subunit e1/e2, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007035 vacuolar acidification ISS
 biological_processGO:0008286 insulin receptor signaling pathway TAS
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0016241 regulation of macroautophagy NAS
 biological_processGO:0033572 transferrin transport TAS
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0090383 phagosome acidification TAS
 biological_processGO:1902600 proton transmembrane transport IGI
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane TAS
 cellular_componentGO:0033179 proton-transporting V-type ATPase, V0 domain IEA
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042625 ATPase coupled ion transmembrane transporter activity ISS
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IBA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000113732 O15342 / ATP6V0E1 / ATPase H+ transporting V0 subunit e1  / complex






 

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