ENSG00000114383


Homo sapiens

Features
Gene ID: ENSG00000114383
  
Biological name :TUSC2
  
Synonyms : O75896 / tumor suppressor candidate 2 / TUSC2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.31
Gene start: 50320027
Gene end: 50328251
  
Corresponding Affymetrix probe sets: 203272_s_at (Human Genome U133 Plus 2.0 Array)   203273_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000399199
Ensembl peptide - ENSP00000409488
Ensembl peptide - ENSP00000232496
Ensembl peptide - ENSP00000394844
NCBI entrez gene - 11334     See in Manteia.
OMIM - 607052
RefSeq - NM_007275
RefSeq Peptide - NP_009206
swissprot - F2Z2A9
swissprot - G3V0I0
swissprot - O75896
Ensembl - ENSG00000114383
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tusc2aENSDARG00000099817Danio rerio
 tusc2bENSDARG00000025340Danio rerio
 TUSC2ENSGALG00000041338Gallus gallus
 Tusc2ENSMUSG00000010054Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029393  Tumour suppressor candidate 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001779 natural killer cell differentiation IEA
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0032618 interleukin-15 production IEA
 biological_processGO:0032700 negative regulation of interleukin-17 production IEA
 biological_processGO:0032733 positive regulation of interleukin-10 production IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IEA
 biological_processGO:0051881 regulation of mitochondrial membrane potential IEA
 biological_processGO:0052567 response to defense-related host reactive oxygen species production IEA
 biological_processGO:0070945 neutrophil mediated killing of gram-negative bacterium IEA
 biological_processGO:0071609 chemokine (C-C motif) ligand 5 production IEA
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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