ENSG00000114520


Homo sapiens

Features
Gene ID: ENSG00000114520
  
Biological name :SNX4
  
Synonyms : O95219 / SNX4 / sorting nexin 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q21.2
Gene start: 125446644
Gene end: 125520197
  
Corresponding Affymetrix probe sets: 205329_s_at (Human Genome U133 Plus 2.0 Array)   212652_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000251775
Ensembl peptide - ENSP00000420175
Ensembl peptide - ENSP00000420526
NCBI entrez gene - 8723     See in Manteia.
OMIM - 605931
RefSeq - XM_017007414
RefSeq - NM_003794
RefSeq Peptide - NP_003785
swissprot - F8W9T3
swissprot - O95219
swissprot - F8WDD4
Ensembl - ENSG00000114520
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snx4ENSDARG00000022659Danio rerio
 SNX4ENSGALG00000012052Gallus gallus
 Snx4ENSMUSG00000022808Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SNX30 / Q5VWJ9 / sorting nexin family member 30ENSG0000014815822
SNX7 / Q9UNH6 / sorting nexin 7ENSG0000016262722


Protein motifs (from Interpro)
Interpro ID Name
 IPR001683  Phox homologous domain
 IPR027267  AH/BAR domain superfamily
 IPR034783  Sorting nexin-4
 IPR034902  Sorting nexin 4, PX domain
 IPR036871  PX domain superfamily
 IPR037430  Sorting nexin-4, BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016050 vesicle organization IBA
 biological_processGO:0032456 endocytic recycling IMP
 biological_processGO:1903595 positive regulation of histamine secretion by mast cell IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005868 cytoplasmic dynein complex IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IBA
 cellular_componentGO:0031201 SNARE complex IDA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IDA
 molecular_functionGO:0005158 insulin receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:1990459 transferrin receptor binding IDA
 molecular_functionGO:1990460 leptin receptor binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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