ENSG00000114771


Homo sapiens

Features
Gene ID: ENSG00000114771
  
Biological name :AADAC
  
Synonyms : AADAC / arylacetamide deacetylase / P22760
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q25.1
Gene start: 151814037
Gene end: 151828488
  
Corresponding Affymetrix probe sets: 205969_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000232892
Ensembl peptide - ENSP00000419620
NCBI entrez gene - 13     See in Manteia.
OMIM - 600338
RefSeq - NM_001086
RefSeq - XM_005247104
RefSeq Peptide - NP_001077
swissprot - C9K0E9
swissprot - P22760
Ensembl - ENSG00000114771
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aadacENSDARG00000063621Danio rerio
 ENSGALG00000010364Gallus gallus
 AadacENSMUSG00000027761Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P093 / AADACL2 / arylacetamide deacetylase like 2ENSG0000019795351
NCEH1 / Q6PIU2 / neutral cholesterol ester hydrolase 1ENSG0000014495943
Q5VUY2 / AADACL4 / arylacetamide deacetylase like 4ENSG0000020451831
Q5VUY0 / AADACL3 / arylacetamide deacetylase like 3ENSG0000018898430


Protein motifs (from Interpro)
Interpro ID Name
 IPR013094  Alpha/beta hydrolase fold-3
 IPR017157  Arylacetamide deacetylase
 IPR029058  Alpha/Beta hydrolase fold
 IPR033140  Lipase, GDXG, putative serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009056 catabolic process IBA
 biological_processGO:0010898 positive regulation of triglyceride catabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003824 catalytic activity TAS
 molecular_functionGO:0004806 triglyceride lipase activity IBA
 molecular_functionGO:0016298 lipase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017171 serine hydrolase activity IDA
 molecular_functionGO:0019213 deacetylase activity TAS
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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