ENSG00000115091


Homo sapiens

Features
Gene ID: ENSG00000115091
  
Biological name :ACTR3
  
Synonyms : ACTR3 / ARP3 actin related protein 3 homolog / P61158
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q14.1
Gene start: 113889960
Gene end: 113962596
  
Corresponding Affymetrix probe sets: 200996_at (Human Genome U133 Plus 2.0 Array)   213101_s_at (Human Genome U133 Plus 2.0 Array)   213102_at (Human Genome U133 Plus 2.0 Array)   228603_at (Human Genome U133 Plus 2.0 Array)   239170_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394213
Ensembl peptide - ENSP00000444987
Ensembl peptide - ENSP00000407912
Ensembl peptide - ENSP00000403125
Ensembl peptide - ENSP00000263238
NCBI entrez gene - 10096     See in Manteia.
OMIM - 604222
RefSeq - NM_001277140
RefSeq - NM_005721
RefSeq Peptide - NP_001264069
RefSeq Peptide - NP_005712
swissprot - B4DXW1
swissprot - P61158
swissprot - A0A024RAI1
swissprot - F8WDR7
swissprot - F8WE84
swissprot - F8WEW2
Ensembl - ENSG00000115091
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 actr3ENSDARG00000091138Danio rerio
 ACTR3ENSGALG00000012159Gallus gallus
 Actr3ENSMUSG00000026341Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACTR3B / Q9P1U1 / ARP3 actin related protein 3 homolog BENSG0000013362790
ACTR3C / Q9C0K3 / ARP3 actin related protein 3 homolog CENSG0000010652640


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR015623  Actin-related protein 3
 IPR020902  Actin/actin-like conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007163 establishment or maintenance of cell polarity IEA
 biological_processGO:0008356 asymmetric cell division IEA
 biological_processGO:0016344 meiotic chromosome movement towards spindle pole IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0033206 meiotic cytokinesis IEA
 biological_processGO:0034314 Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 biological_processGO:0048013 ephrin receptor signaling pathway TAS
 biological_processGO:0051321 meiotic cell cycle IEA
 biological_processGO:0051653 spindle localization IEA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0070358 actin polymerization-dependent cell motility TAS
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005885 Arp2/3 protein complex IEA
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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