ENSG00000115368


Homo sapiens

Features
Gene ID: ENSG00000115368
  
Biological name :WDR75
  
Synonyms : Q8IWA0 / WDR75 / WD repeat domain 75
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q32.2
Gene start: 189441433
Gene end: 189475565
  
Corresponding Affymetrix probe sets: 224721_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000314193
Ensembl peptide - ENSP00000400728
Ensembl peptide - ENSP00000414226
Ensembl peptide - ENSP00000486831
NCBI entrez gene - 84128     See in Manteia.
RefSeq - NM_032168
RefSeq - NM_001303096
RefSeq Peptide - NP_001290025
RefSeq Peptide - NP_115544
swissprot - Q8IWA0
swissprot - F8WC81
swissprot - F8WE20
Ensembl - ENSG00000115368
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdr75ENSDARG00000040730Danio rerio
 ENSGALG00000045237Gallus gallus
 ENSGALG00000042197Gallus gallus
 Wdr75ENSMUSG00000025995Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0045943 positive regulation of transcription by RNA polymerase I IMP
 biological_processGO:1903146 regulation of autophagy of mitochondrion IMP
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 biological_processGO:2000234 positive regulation of rRNA processing IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
rRNA modification in the nucleus and cytosol
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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