ENSG00000116209


Homo sapiens

Features
Gene ID: ENSG00000116209
  
Biological name :TMEM59
  
Synonyms : Q9BXS4 / TMEM59 / transmembrane protein 59
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 54026681
Gene end: 54053504
  
Corresponding Affymetrix probe sets: 200620_at (Human Genome U133 Plus 2.0 Array)   228835_at (Human Genome U133 Plus 2.0 Array)   241018_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413792
Ensembl peptide - ENSP00000234831
Ensembl peptide - ENSP00000360388
Ensembl peptide - ENSP00000360392
Ensembl peptide - ENSP00000360395
Ensembl peptide - ENSP00000360399
Ensembl peptide - ENSP00000397772
Ensembl peptide - ENSP00000399761
NCBI entrez gene - 9528     See in Manteia.
OMIM - 617084
RefSeq - XM_006711051
RefSeq - NM_001305043
RefSeq - NM_001305049
RefSeq - NM_001305050
RefSeq - NM_001305051
RefSeq - NM_001305052
RefSeq - NM_001305066
RefSeq - NM_004872
RefSeq Peptide - NP_001291978
RefSeq Peptide - NP_001291979
RefSeq Peptide - NP_001291980
RefSeq Peptide - NP_001291981
RefSeq Peptide - NP_001291995
RefSeq Peptide - NP_004863
RefSeq Peptide - NP_001291972
swissprot - Q5T703
swissprot - Q5T704
swissprot - Q5T706
swissprot - Q9BXS4
swissprot - Q5T6Z8
Ensembl - ENSG00000116209
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem59ENSDARG00000019033Danio rerio
 TMEM59ENSGALG00000010746Gallus gallus
 Q9QY73ENSMUSG00000028618Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UK28 / TMEM59L / transmembrane protein 59 likeENSG0000010569632


Protein motifs (from Interpro)
Interpro ID Name
 IPR022065  Uncharacterised protein family, TMEM59


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0010955 negative regulation of protein processing IDA
 biological_processGO:0090285 negative regulation of protein glycosylation in Golgi IDA
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IDA
 cellular_componentGO:0000137 Golgi cis cisterna IDA
 cellular_componentGO:0000138 Golgi trans cisterna IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005797 Golgi medial cisterna IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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