ENSG00000116285


Homo sapiens

Features
Gene ID: ENSG00000116285
  
Biological name :ERRFI1
  
Synonyms : ERBB receptor feedback inhibitor 1 / ERRFI1 / Q9UJM3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.23
Gene start: 8004404
Gene end: 8026308
  
Corresponding Affymetrix probe sets: 224657_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465100
Ensembl peptide - ENSP00000466958
Ensembl peptide - ENSP00000467030
Ensembl peptide - ENSP00000366702
Ensembl peptide - ENSP00000466454
NCBI entrez gene - 54206     See in Manteia.
OMIM - 608069
RefSeq - XM_011541596
RefSeq - NM_018948
RefSeq - XM_005263477
RefSeq - XM_006710697
RefSeq Peptide - NP_061821
swissprot - I6S2Y9
swissprot - K7ENN7
swissprot - K7EJB4
swissprot - K7EMD2
swissprot - K7ENI4
swissprot - Q9UJM3
Ensembl - ENSG00000116285
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 errfi1aENSDARG00000104039Danio rerio
 ERRFI1ENSGALG00000000535Gallus gallus
 Errfi1ENSMUSG00000028967Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021619  Mig-6 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007175 negative regulation of epidermal growth factor-activated receptor activity ISS
 biological_processGO:0031953 negative regulation of protein autophosphorylation IDA
 biological_processGO:0032691 negative regulation of interleukin-1 beta production IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0032966 negative regulation of collagen biosynthetic process IEA
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IEA
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0042536 negative regulation of tumor necrosis factor biosynthetic process IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0043589 skin morphogenesis ISS
 biological_processGO:0045616 regulation of keratinocyte differentiation IBA
 biological_processGO:0048286 lung alveolus development ISS
 biological_processGO:0050732 negative regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0060426 lung vasculature development ISS
 biological_processGO:0060428 lung epithelium development ISS
 biological_processGO:0061469 regulation of type B pancreatic cell proliferation IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0071474 cellular hyperosmotic response IEA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031267 small GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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