ENSG00000116649


Homo sapiens

Features
Gene ID: ENSG00000116649
  
Biological name :SRM
  
Synonyms : P19623 / spermidine synthase / SRM
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.22
Gene start: 11054584
Gene end: 11060024
  
Corresponding Affymetrix probe sets: 201516_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465687
Ensembl peptide - ENSP00000467669
Ensembl peptide - ENSP00000468760
Ensembl peptide - ENSP00000366156
Ensembl peptide - ENSP00000465966
NCBI entrez gene - 6723     See in Manteia.
OMIM - 182891
RefSeq - XM_017002179
RefSeq - NM_003132
RefSeq Peptide - NP_003123
swissprot - K7EQ47
swissprot - K7ESL0
swissprot - K7EKM4
swissprot - P19623
swissprot - K7EL89
Ensembl - ENSG00000116649
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srmENSDARG00000055760Danio rerio
 SRMENSGALG00000003039Gallus gallus
 SrmENSMUSG00000006442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001045  Spermidine/spermine synthases
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR030373  Polyamine biosynthesis domain, conserved site
 IPR030374  Polyamine biosynthesis domain
 IPR030668  Spermidine/spermine synthase, eukaryotes
 IPR035246  Spermidine synthase, tetramerisation domain
 IPR037163  Spermidine synthase, tetramerisation domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006595 polyamine metabolic process TAS
 biological_processGO:0006596 polyamine biosynthetic process IEA
 biological_processGO:0008295 spermidine biosynthetic process IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004766 spermidine synthase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Metabolism of polyamines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr