ENSG00000116771


Homo sapiens

Features
Gene ID: ENSG00000116771
  
Biological name :AGMAT
  
Synonyms : AGMAT / agmatinase / Q9BSE5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.21
Gene start: 15572353
Gene end: 15585110
  
Corresponding Affymetrix probe sets: 219792_at (Human Genome U133 Plus 2.0 Array)   221648_s_at (Human Genome U133 Plus 2.0 Array)   222930_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364986
NCBI entrez gene - 79814     See in Manteia.
RefSeq - NM_024758
RefSeq Peptide - NP_079034
swissprot - A0A024QZ78
swissprot - Q9BSE5
Ensembl - ENSG00000116771
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agmatENSDARG00000059700Danio rerio
 AGMATENSGALG00000031872Gallus gallus
 AgmatENSMUSG00000040706Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARG2 / P78540 / arginase 2ENSG0000008118123
ARG1 / P05089 / arginase 1ENSG0000011852021


Protein motifs (from Interpro)
Interpro ID Name
 IPR005925  Agmatinase-related
 IPR006035  Ureohydrolase
 IPR020855  Ureohydrolase, manganese-binding site
 IPR023696  Ureohydrolase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008295 spermidine biosynthetic process IEA
 biological_processGO:0009446 putrescine biosynthetic process IEA
 biological_processGO:0033388 putrescine biosynthetic process from arginine IEA
 biological_processGO:0097055 agmatine biosynthetic process TAS
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008783 agmatinase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Agmatine biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr