ENSG00000116809


Homo sapiens

Features
Gene ID: ENSG00000116809
  
Biological name :ZBTB17
  
Synonyms : Q13105 / ZBTB17 / zinc finger and BTB domain containing 17
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.13
Gene start: 15941869
Gene end: 15976132
  
Corresponding Affymetrix probe sets: 203601_s_at (Human Genome U133 Plus 2.0 Array)   203602_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364895
Ensembl peptide - ENSP00000408483
Ensembl peptide - ENSP00000438529
Ensembl peptide - ENSP00000364885
Ensembl peptide - ENSP00000400827
NCBI entrez gene - 7709     See in Manteia.
OMIM - 604084
RefSeq - XM_017002242
RefSeq - NM_001324137
RefSeq - NM_001324138
RefSeq - NM_003443
RefSeq - XM_005245986
RefSeq - XM_005245987
RefSeq - XM_011542085
RefSeq - XM_011542086
RefSeq - XM_011542087
RefSeq - XM_011542088
RefSeq - NM_001242884
RefSeq - NM_001287603
RefSeq - NM_001287604
RefSeq Peptide - NP_001274532
RefSeq Peptide - NP_001274533
RefSeq Peptide - NP_001311066
RefSeq Peptide - NP_001311067
RefSeq Peptide - NP_003434
RefSeq Peptide - NP_001229813
swissprot - H0Y6X2
swissprot - H7C1K8
swissprot - Q13105
Ensembl - ENSG00000116809
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zbtb17ENSDARG00000074548Danio rerio
 ZBTB17ENSGALG00000035352Gallus gallus
 Q60821ENSMUSG00000006215Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O43167 / ZBTB24 / zinc finger and BTB domain containing 24ENSG0000011236521
P52739 / ZNF131 / zinc finger protein 131ENSG0000017226219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001702 gastrulation with mouth forming second IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007398 ectoderm development IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 biological_processGO:0045786 negative regulation of cell cycle TAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0071158 positive regulation of cell cycle arrest IDA
 biological_processGO:1903146 regulation of autophagy of mitochondrion IMP
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0032993 protein-DNA complex IMP
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001047 core promoter binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001223 transcription coactivator binding IPI
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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