ENSG00000116815


Homo sapiens

Features
Gene ID: ENSG00000116815
  
Biological name :CD58
  
Synonyms : CD58 / CD58 molecule / P19256
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.1
Gene start: 116514535
Gene end: 116571039
  
Corresponding Affymetrix probe sets: 205173_x_at (Human Genome U133 Plus 2.0 Array)   211744_s_at (Human Genome U133 Plus 2.0 Array)   216322_at (Human Genome U133 Plus 2.0 Array)   216942_s_at (Human Genome U133 Plus 2.0 Array)   222061_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432773
Ensembl peptide - ENSP00000433648
Ensembl peptide - ENSP00000358499
Ensembl peptide - ENSP00000358501
Ensembl peptide - ENSP00000409080
NCBI entrez gene - 965     See in Manteia.
OMIM - 153420
RefSeq - NM_001779
RefSeq - XM_017002869
RefSeq - NM_001144822
RefSeq Peptide - NP_001138294
RefSeq Peptide - NP_001770
swissprot - H0YDI1
swissprot - P19256
swissprot - B1AMW1
Ensembl - ENSG00000116815
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion NAS
 biological_processGO:0034113 heterotypic cell-cell adhesion IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0098609 cell-cell adhesion NAS
 biological_processGO:2000484 positive regulation of interleukin-8 secretion IMP
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane NAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116824 CD2 / P06729 / CD2 molecule  / reaction / complex






 

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contact: otassy@igbmc.fr