ENSG00000116903


Homo sapiens

Features
Gene ID: ENSG00000116903
  
Biological name :EXOC8
  
Synonyms : EXOC8 / exocyst complex component 8 / Q8IYI6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q42.2
Gene start: 231332753
Gene end: 231337852
  
Corresponding Affymetrix probe sets: 227577_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355605
NCBI entrez gene - 149371     See in Manteia.
OMIM - 615283
RefSeq - NM_175876
RefSeq Peptide - NP_787072
swissprot - Q8IYI6
Ensembl - ENSG00000116903
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exoc8ENSDARG00000063211Danio rerio
 EXOC8ENSGALG00000043280Gallus gallus
 Exoc8ENSMUSG00000074030Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR016159  Cullin repeat-like-containing domain superfamily
 IPR032403  Exocyst component Exo84, C-terminal
 IPR033961  Exocyst complex component Exo84


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001927 exocyst assembly IBA
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0007032 endosome organization IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0022617 extracellular matrix disassembly IMP
 biological_processGO:0034613 cellular protein localization IEA
 biological_processGO:0051601 exocyst localization IBA
 cellular_componentGO:0000145 exocyst IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017160 Ral GTPase binding IPI


Pathways (from Reactome)
Pathway description
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Insulin processing
VxPx cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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