ENSG00000116981


Homo sapiens

Features
Gene ID: ENSG00000116981
  
Biological name :NT5C1A
  
Synonyms : 5-nucleotidase, cytosolic IA / NT5C1A / Q9BXI3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.2
Gene start: 39659121
Gene end: 39672038
  
Corresponding Affymetrix probe sets: 224529_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000235628
NCBI entrez gene - 84618     See in Manteia.
OMIM - 610525
RefSeq - NM_032526
RefSeq Peptide - NP_115915
swissprot - Q9BXI3
Ensembl - ENSG00000116981
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nt5c1aaENSDARG00000035883Danio rerio
 nt5c1abENSDARG00000070590Danio rerio
 NT5C1AENSGALG00000003816Gallus gallus
 A3KFX0ENSMUSG00000054958Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NT5C1B / Q96P26 / 5-nucleotidase, cytosolic IBENSG0000018501361
NT5C1B-RDH14 / NT5C1B-RDH14 readthroughENSG0000025074160


Protein motifs (from Interpro)
Interpro ID Name
 IPR010394  5-nucleotidase
 IPR023214  HAD superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006195 purine nucleotide catabolic process TAS
 biological_processGO:0009116 nucleoside metabolic process NAS
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0009128 purine nucleoside monophosphate catabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0046085 adenosine metabolic process IEA
 biological_processGO:0046135 pyrimidine nucleoside catabolic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008253 5"-nucleotidase activity EXP
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Pyrimidine catabolism
Purine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116981 NT5C1A / Q9BXI3 / 5-nucleotidase, cytosolic IA  / complex






 

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