ENSG00000117543


Homo sapiens

Features
Gene ID: ENSG00000117543
  
Biological name :DPH5
  
Synonyms : diphthamide biosynthesis 5 / DPH5 / Q9H2P9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p21.2
Gene start: 100989623
Gene end: 101026088
  
Corresponding Affymetrix probe sets: 219590_x_at (Human Genome U133 Plus 2.0 Array)   222360_at (Human Genome U133 Plus 2.0 Array)   223671_x_at (Human Genome U133 Plus 2.0 Array)   224060_s_at (Human Genome U133 Plus 2.0 Array)   224196_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000339630
Ensembl peptide - ENSP00000359127
Ensembl peptide - ENSP00000394364
Ensembl peptide - ENSP00000418282
NCBI entrez gene - 51611     See in Manteia.
OMIM - 611075
RefSeq - XM_017001462
RefSeq - NM_001077394
RefSeq - NM_001077395
RefSeq - NM_015958
RefSeq - XM_006710683
RefSeq - XM_011541569
RefSeq - XM_011541570
RefSeq - XM_017001460
RefSeq - XM_017001461
RefSeq - XM_005270938
RefSeq - XM_005270939
RefSeq - XM_005270941
RefSeq Peptide - NP_001070863
RefSeq Peptide - NP_057042
RefSeq Peptide - NP_001070862
swissprot - Q96DC6
swissprot - Q9H2P9
Ensembl - ENSG00000117543
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dph5ENSDARG00000100242Danio rerio
 DPH5ENSGALG00000005229Gallus gallus
 Dph5ENSMUSG00000033554Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000878  Tetrapyrrole methylase
 IPR004551  Diphthine synthase
 IPR014776  Tetrapyrrole methylase, subdomain 2
 IPR014777  Tetrapyrrole methylase, subdomain 1
 IPR035996  Tetrapyrrole methylase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine IBA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004164 diphthine synthase activity EXP
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of diphthamide-EEF2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000167658 EEF2 / P13639 / eukaryotic translation elongation factor 2  / reaction






 

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