ENSMUSG00000033554


Mus musculus

Features
Gene ID: ENSMUSG00000033554
  
Biological name :Dph5
  
Synonyms : Diphthine methyl ester synthase / Dph5 / Q9CWQ0
  
Possible biological names infered from orthology : diphthamide biosynthesis 5 / Q9H2P9
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: G1
Gene start: 115887837
Gene end: 115934361
  
Corresponding Affymetrix probe sets: 10495530 (MoGene1.0st)   1439049_at (Mouse Genome 430 2.0 Array)   1452839_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142654
Ensembl peptide - ENSMUSP00000143049
Ensembl peptide - ENSMUSP00000043730
Ensembl peptide - ENSMUSP00000102114
Ensembl peptide - ENSMUSP00000139249
Ensembl peptide - ENSMUSP00000140958
NCBI entrez gene - 69740     See in Manteia.
MGI - MGI:1916990
RefSeq - NM_027193
RefSeq - XM_006502039
RefSeq Peptide - NP_081469
swissprot - Q8BG20
swissprot - A0A0G2JE69
swissprot - Q9CWQ0
swissprot - V9GXP1
Ensembl - ENSMUSG00000033554
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dph5ENSDARG00000100242Danio rerio
 DPH5ENSGALG00000005229Gallus gallus
 DPH5ENSG00000117543Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000878  Tetrapyrrole methylase
 IPR004551  Diphthine synthase
 IPR014776  Tetrapyrrole methylase, subdomain 2
 IPR014777  Tetrapyrrole methylase, subdomain 1
 IPR035996  Tetrapyrrole methylase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine IBA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004164 diphthine synthase activity ISO
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of diphthamide-EEF2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000034994 Eef2 / P58252 / Elongation factor 2 / P13639* / eukaryotic translation elongation factor 2*  / reaction






 

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contact: otassy@igbmc.fr