ENSG00000117751


Homo sapiens

Features
Gene ID: ENSG00000117751
  
Biological name :PPP1R8
  
Synonyms : PPP1R8 / protein phosphatase 1 regulatory subunit 8 / Q12972
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.3
Gene start: 27830778
Gene end: 27851676
  
Corresponding Affymetrix probe sets: 207830_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000410206
Ensembl peptide - ENSP00000236412
Ensembl peptide - ENSP00000311677
Ensembl peptide - ENSP00000363042
NCBI entrez gene - 5511     See in Manteia.
OMIM - 602636
RefSeq - XM_017001594
RefSeq - NM_002713
RefSeq - NM_014110
RefSeq - NM_138558
RefSeq Peptide - NP_002704
RefSeq Peptide - NP_054829
RefSeq Peptide - NP_612568
swissprot - Q12972
swissprot - Q6ICT4
swissprot - A0A0A0MT09
Ensembl - ENSG00000117751
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1r8aENSDARG00000007186Danio rerio
 ppp1r8bENSDARG00000022430Danio rerio
 PPP1R8ENSGALG00000000729Gallus gallus
 Ppp1r8ENSMUSG00000028882Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BWU0 / SLC4A1AP / solute carrier family 4 member 1 adaptor proteinENSG0000016379823
SNIP1 / Q8TAD8 / Smad nuclear interacting protein 1ENSG0000016387712


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR008984  SMAD/FHA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006401 RNA catabolic process TAS
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0035308 negative regulation of protein dephosphorylation IBA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0004865 protein serine/threonine phosphatase inhibitor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008995 ribonuclease E activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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