ENSG00000119185


Homo sapiens

Features
Gene ID: ENSG00000119185
  
Biological name :ITGB1BP1
  
Synonyms : integrin subunit beta 1 binding protein 1 / ITGB1BP1 / O14713
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p25.1
Gene start: 9403475
Gene end: 9423547
  
Corresponding Affymetrix probe sets: 203336_s_at (Human Genome U133 Plus 2.0 Array)   203337_x_at (Human Genome U133 Plus 2.0 Array)   228227_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417940
Ensembl peptide - ENSP00000417850
Ensembl peptide - ENSP00000418526
Ensembl peptide - ENSP00000433814
Ensembl peptide - ENSP00000420770
Ensembl peptide - ENSP00000419814
Ensembl peptide - ENSP00000419524
Ensembl peptide - ENSP00000419452
Ensembl peptide - ENSP00000418947
Ensembl peptide - ENSP00000238091
Ensembl peptide - ENSP00000347504
Ensembl peptide - ENSP00000352743
Ensembl peptide - ENSP00000353850
Ensembl peptide - ENSP00000389704
NCBI entrez gene - 9270     See in Manteia.
OMIM - 607153
RefSeq - XM_017005270
RefSeq - NM_001319066
RefSeq - NM_001319067
RefSeq - NM_001319068
RefSeq - NM_001319069
RefSeq - NM_001319070
RefSeq - NM_004763
RefSeq - NM_022334
RefSeq - XM_005246183
RefSeq - XM_005246184
RefSeq - XM_005246185
RefSeq - XM_005246189
RefSeq - XM_006711903
RefSeq - XM_011510416
RefSeq - XM_017005267
RefSeq - XM_017005268
RefSeq - XM_017005269
RefSeq Peptide - NP_001305996
RefSeq Peptide - NP_001305997
RefSeq Peptide - NP_001305998
RefSeq Peptide - NP_001305999
RefSeq Peptide - NP_004754
RefSeq Peptide - NP_071729
RefSeq Peptide - NP_001305995
swissprot - F8WF20
swissprot - G3V1A3
swissprot - A8MPU2
swissprot - O14713
swissprot - C9JZ07
swissprot - C9JBU8
swissprot - C9J6Y2
swissprot - C9J5T5
swissprot - C9J0J6
swissprot - C9IZZ8
Ensembl - ENSG00000119185
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itgb1bp1ENSDARG00000007169Danio rerio
 ITGB1BP1ENSGALG00000016421Gallus gallus
 O35671ENSMUSG00000062352Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR019517  Integrin binding protein, ICAP-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IDA
 biological_processGO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration ISS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IDA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0010595 positive regulation of endothelial cell migration IDA
 biological_processGO:0010764 negative regulation of fibroblast migration ISS
 biological_processGO:0015031 protein transport IDA
 biological_processGO:0016477 cell migration TAS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031214 biomineral tissue development IEA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0032148 activation of protein kinase B activity IDA
 biological_processGO:0033622 integrin activation ISS
 biological_processGO:0033628 regulation of cell adhesion mediated by integrin ISS
 biological_processGO:0035148 tube formation IDA
 biological_processGO:0035556 intracellular signal transduction TAS
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IDA
 biological_processGO:0043087 regulation of GTPase activity IDA
 biological_processGO:0043113 receptor clustering ISS
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IDA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0050880 regulation of blood vessel size IDA
 biological_processGO:0051451 myoblast migration ISS
 biological_processGO:0051496 positive regulation of stress fiber assembly ISS
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IEA
 biological_processGO:0051895 negative regulation of focal adhesion assembly IDA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IDA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis IDA
 biological_processGO:0090314 positive regulation of protein targeting to membrane ISS
 biological_processGO:0090315 negative regulation of protein targeting to membrane IDA
 biological_processGO:1900025 negative regulation of substrate adhesion-dependent cell spreading IDA
 biological_processGO:2001044 regulation of integrin-mediated signaling pathway ISS
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton ISS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery IDA
 molecular_functionGO:0005092 GDP-dissociation inhibitor activity IDA
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008565 protein transporter activity IDA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr