ENSG00000119383


Homo sapiens

Features
Gene ID: ENSG00000119383
  
Biological name :PTPA
  
Synonyms : protein phosphatase 2 phosphatase activator / PTPA / Q15257
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q34.11
Gene start: 129110950
Gene end: 129148946
  
Corresponding Affymetrix probe sets: 206452_x_at (Human Genome U133 Plus 2.0 Array)   208874_x_at (Human Genome U133 Plus 2.0 Array)   216105_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395499
Ensembl peptide - ENSP00000416661
Ensembl peptide - ENSP00000416522
Ensembl peptide - ENSP00000411604
Ensembl peptide - ENSP00000408726
Ensembl peptide - ENSP00000408316
Ensembl peptide - ENSP00000406997
Ensembl peptide - ENSP00000405100
Ensembl peptide - ENSP00000403542
Ensembl peptide - ENSP00000400314
Ensembl peptide - ENSP00000399069
Ensembl peptide - ENSP00000396660
Ensembl peptide - ENSP00000335200
Ensembl peptide - ENSP00000337412
Ensembl peptide - ENSP00000337448
Ensembl peptide - ENSP00000347109
Ensembl peptide - ENSP00000349726
Ensembl peptide - ENSP00000351885
Ensembl peptide - ENSP00000377036
Ensembl peptide - ENSP00000387726
Ensembl peptide - ENSP00000389312
Ensembl peptide - ENSP00000393092
Ensembl peptide - ENSP00000393196
Ensembl peptide - ENSP00000393796
Ensembl peptide - ENSP00000394001
Ensembl peptide - ENSP00000394338
NCBI entrez gene - 5524     See in Manteia.
OMIM - 600756
RefSeq - XM_017014888
RefSeq - NM_001193397
RefSeq - NM_001271832
RefSeq - NM_021131
RefSeq - NM_178000
RefSeq - NM_178001
RefSeq - NM_178003
RefSeq - XM_011518834
RefSeq - XM_011518835
RefSeq - XM_011518836
RefSeq - XM_011518837
RefSeq - XM_011518838
RefSeq Peptide - NP_821068
RefSeq Peptide - NP_821070
RefSeq Peptide - NP_001180326
RefSeq Peptide - NP_001258761
RefSeq Peptide - NP_066954
RefSeq Peptide - NP_821067
swissprot - B7ZBP9
swissprot - B7ZBP7
swissprot - B4DDQ6
swissprot - A6PVN9
swissprot - A6PVN8
swissprot - A6PVN7
swissprot - A6PVN6
swissprot - A6PVN5
swissprot - B7ZBQ0
swissprot - F6WIT2
swissprot - H0Y6E5
swissprot - H0Y562
swissprot - Q15257
swissprot - Q5T948
swissprot - Q5T949
swissprot - Q68CR8
swissprot - C9IZ76
Ensembl - ENSG00000119383
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptpaENSDARG00000031985Danio rerio
 PTPAENSGALG00000036965Gallus gallus
 PtpaENSMUSG00000039515Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004327  Phosphotyrosyl phosphatase activator, PTPA
 IPR037218  PTPA superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IDA
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity IDA
 biological_processGO:0035307 positive regulation of protein dephosphorylation IDA
 biological_processGO:0035308 negative regulation of protein dephosphorylation IDA
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IDA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0034704 calcium channel complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008160 protein tyrosine phosphatase activator activity TAS
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0019211 phosphatase activator activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity TAS
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity TAS
 molecular_functionGO:0051721 protein phosphatase 2A binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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