ENSMUSG00000039515


Mus musculus

Features
Gene ID: ENSMUSG00000039515
  
Biological name :Ptpa
  
Synonyms : P58389 / protein phosphatase 2 protein activator / Ptpa
  
Possible biological names infered from orthology : protein phosphatase 2 phosphatase activator / Q15257
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 30416039
Gene end: 30447806
  
Corresponding Affymetrix probe sets: 10471045 (MoGene1.0st)   1439383_x_at (Mouse Genome 430 2.0 Array)   1439393_x_at (Mouse Genome 430 2.0 Array)   1448138_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109233
Ensembl peptide - ENSMUSP00000117121
Ensembl peptide - ENSMUSP00000116268
Ensembl peptide - ENSMUSP00000114985
Ensembl peptide - ENSMUSP00000114290
Ensembl peptide - ENSMUSP00000046837
Ensembl peptide - ENSMUSP00000109231
NCBI entrez gene - 110854     See in Manteia.
MGI - MGI:1346006
RefSeq - XM_006497608
RefSeq - NM_138748
RefSeq Peptide - NP_620087
swissprot - F6Z6I0
swissprot - B7ZDE0
swissprot - D6RFC2
swissprot - P58389
swissprot - Q543N6
swissprot - A2AWE9
swissprot - A2AWF0
Ensembl - ENSMUSG00000039515
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptpaENSDARG00000031985Danio rerio
 PTPAENSGALG00000036965Gallus gallus
 PTPAENSG00000119383Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004327  Phosphotyrosyl phosphatase activator, PTPA
 IPR037218  PTPA superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0035307 positive regulation of protein dephosphorylation IEA
 biological_processGO:0035308 negative regulation of protein dephosphorylation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0034704 calcium channel complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005524 ATP binding ISS
 molecular_functionGO:0008160 protein tyrosine phosphatase activator activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0019211 phosphatase activator activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ptchd1tm1b(KOMP)IcsOrl/Ptchd1tm1b(KOMP)IcsOrl
Genetic Background: C57BL/6N-Ptchd1tm1b(KOMP)IcsOrl/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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