ENSG00000120253


Homo sapiens

Features
Gene ID: ENSG00000120253
  
Biological name :NUP43
  
Synonyms : nucleoporin 43 / NUP43 / Q8NFH3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q25.1
Gene start: 149724315
Gene end: 149749665
  
Corresponding Affymetrix probe sets: 219007_at (Human Genome U133 Plus 2.0 Array)   238474_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000438031
Ensembl peptide - ENSP00000356372
Ensembl peptide - ENSP00000356374
Ensembl peptide - ENSP00000385078
Ensembl peptide - ENSP00000342262
NCBI entrez gene - 348995     See in Manteia.
OMIM - 608141
RefSeq - XM_011535799
RefSeq - NM_198887
RefSeq - XM_005266960
RefSeq - XM_005266961
RefSeq - XM_005266962
RefSeq - XM_011535798
RefSeq Peptide - NP_942590
swissprot - B4E301
swissprot - F5H0E3
swissprot - B4DVD1
swissprot - Q8NFH3
Ensembl - ENSG00000120253
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup43ENSDARG00000043884Danio rerio
 NUP43ENSGALG00000012387Gallus gallus
 Nup43ENSMUSG00000040034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031080 nuclear pore outer ring IEA
 cellular_componentGO:0043657 host cell IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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