ENSG00000122122


Homo sapiens

Features
Gene ID: ENSG00000122122
  
Biological name :SASH3
  
Synonyms : O75995 / SAM and SH3 domain containing 3 / SASH3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q26.1
Gene start: 129779979
Gene end: 129795201
  
Corresponding Affymetrix probe sets: 204923_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000349359
NCBI entrez gene - 54440     See in Manteia.
OMIM - 300441
RefSeq - NM_018990
RefSeq - XM_006724763
RefSeq Peptide - NP_061863
swissprot - O75995
Ensembl - ENSG00000122122
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sash3ENSDARG00000016541Danio rerio
 SASH3ENSGALG00000032530Gallus gallus
 Sash3ENSMUSG00000031101Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SASH1 / O94885 / SAM and SH3 domain containing 1ENSG0000011196141
Q9NSI8 / SAMSN1 / SAM domain, SH3 domain and nuclear localization signals 1ENSG0000015530739


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001660  Sterile alpha motif domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR021090  SAM/SH3 domain-containing
 IPR035721  SAM and SH3 domain-containing protein 3, SH3 domain
 IPR035722  SAM and SH3 domain-containing protein 3
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002639 positive regulation of immunoglobulin production IEA
 biological_processGO:0002726 positive regulation of T cell cytokine production IEA
 biological_processGO:0002821 positive regulation of adaptive immune response IEA
 biological_processGO:0030890 positive regulation of B cell proliferation IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032733 positive regulation of interleukin-10 production IEA
 biological_processGO:0032743 positive regulation of interleukin-2 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production IEA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0046622 positive regulation of organ growth IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0051251 positive regulation of lymphocyte activation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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