ENSG00000122188


Homo sapiens

Features
Gene ID: ENSG00000122188
  
Biological name :LAX1
  
Synonyms : LAX1 / lymphocyte transmembrane adaptor 1 / Q8IWV1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 203765176
Gene end: 203776233
  
Corresponding Affymetrix probe sets: 207734_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406970
Ensembl peptide - ENSP00000356186
NCBI entrez gene - 54900     See in Manteia.
RefSeq - NM_017773
RefSeq - XM_006711397
RefSeq - NM_001136190
RefSeq - NM_001282878
RefSeq Peptide - NP_001269807
RefSeq Peptide - NP_060243
RefSeq Peptide - NP_001129662
swissprot - Q8IWV1
Ensembl - ENSG00000122188
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Lax1ENSMUSG00000051998Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR031393  Lymphocyte transmembrane adapter 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000188 inactivation of MAPK activity IMP
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006955 immune response IDA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0042113 B cell activation IDA
 biological_processGO:0050868 negative regulation of T cell activation IDA
 biological_processGO:0051249 regulation of lymphocyte activation IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IDA
 molecular_functionGO:0042169 SH2 domain binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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