ENSG00000123159


Homo sapiens

Features
Gene ID: ENSG00000123159
  
Biological name :GIPC1
  
Synonyms : GIPC1 / GIPC PDZ domain containing family member 1 / O14908
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.12
Gene start: 14477760
Gene end: 14496149
  
Corresponding Affymetrix probe sets: 207525_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466747
Ensembl peptide - ENSP00000466624
Ensembl peptide - ENSP00000467077
Ensembl peptide - ENSP00000468787
Ensembl peptide - ENSP00000340698
Ensembl peptide - ENSP00000376748
Ensembl peptide - ENSP00000376753
Ensembl peptide - ENSP00000464879
Ensembl peptide - ENSP00000465003
Ensembl peptide - ENSP00000466105
Ensembl peptide - ENSP00000466312
NCBI entrez gene - 10755     See in Manteia.
OMIM - 605072
RefSeq - XM_017026148
RefSeq - NM_005716
RefSeq - NM_202468
RefSeq - NM_202469
RefSeq - NM_202470
RefSeq - NM_202494
RefSeq - XM_017026147
RefSeq Peptide - NP_974198
RefSeq Peptide - NP_974199
RefSeq Peptide - NP_974223
RefSeq Peptide - NP_005707
RefSeq Peptide - NP_974197
swissprot - K7EM11
swissprot - K7ESN1
swissprot - A0A024R7I1
swissprot - K7EIT0
swissprot - K7EJ33
swissprot - K7ELJ2
swissprot - O14908
swissprot - A0A024R7I0
Ensembl - ENSG00000123159
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gipc1ENSDARG00000104483Danio rerio
 Gipc1ENSMUSG00000019433Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GIPC2 / Q8TF65 / GIPC PDZ domain containing family member 2ENSG0000013796059
GIPC3 / Q8TF64 / GIPC PDZ domain containing family member 3ENSG0000017985559


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR017379  PDZ domain-containing protein GIPC1/2/3
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting ISS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway NAS
 biological_processGO:0007268 chemical synaptic transmission ISS
 biological_processGO:0014047 glutamate secretion ISS
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway ISS
 biological_processGO:0031647 regulation of protein stability ISS
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0043542 endothelial cell migration ISS
 biological_processGO:0048167 regulation of synaptic plasticity ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005903 brush border IEA
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0008021 synaptic vesicle ISS
 cellular_componentGO:0012506 vesicle membrane ISS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0043197 dendritic spine ISS
 cellular_componentGO:0043198 dendritic shaft ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003779 actin binding ISS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017022 myosin binding ISS
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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