ENSG00000123219


Homo sapiens

Features
Gene ID: ENSG00000123219
  
Biological name :CENPK
  
Synonyms : CENPK / centromere protein K / Q9BS16
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q12.3
Gene start: 65517766
Gene end: 65563171
  
Corresponding Affymetrix probe sets: 222848_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422421
Ensembl peptide - ENSP00000422365
Ensembl peptide - ENSP00000423308
Ensembl peptide - ENSP00000427648
Ensembl peptide - ENSP00000425686
Ensembl peptide - ENSP00000424686
Ensembl peptide - ENSP00000424450
Ensembl peptide - ENSP00000424039
Ensembl peptide - ENSP00000242872
Ensembl peptide - ENSP00000379911
Ensembl peptide - ENSP00000421034
NCBI entrez gene - 64105     See in Manteia.
OMIM - 611502
RefSeq - XM_017009701
RefSeq - XM_017009690
RefSeq - XM_017009691
RefSeq - XM_017009692
RefSeq - XM_017009693
RefSeq - XM_017009694
RefSeq - XM_017009695
RefSeq - XM_017009696
RefSeq - XM_017009697
RefSeq - XM_017009698
RefSeq - XM_017009699
RefSeq - XM_017009700
RefSeq - NM_001267038
RefSeq - NM_022145
RefSeq - XM_011543534
RefSeq - XM_011543535
RefSeq - XM_011543536
RefSeq - XM_011543537
RefSeq - XM_011543538
RefSeq - XM_011543539
RefSeq - XM_011543540
RefSeq - XM_011543541
RefSeq Peptide - NP_001253967
RefSeq Peptide - NP_001336297
RefSeq Peptide - NP_071428
swissprot - D6RBN6
swissprot - D6RAX0
swissprot - D6RJF0
swissprot - Q9BS16
swissprot - D6R984
swissprot - H0Y9K8
swissprot - D6RHD3
swissprot - D6RC76
Ensembl - ENSG00000123219
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cenpkENSDARG00000039616Danio rerio
 CENPKENSGALG00000014753Gallus gallus
 CenpkENSMUSG00000021714Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR020993  Centromere protein Cenp-K


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0034080 CENP-A containing nucleosome assembly TAS
 biological_processGO:0051382 kinetochore assembly IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000153044 CENPH / Q9H3R5 / centromere protein H  / complex
 ENSG00000102384 CENPI / Q92674 / centromere protein I  / complex






 

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