ENSG00000153044


Homo sapiens

Features
Gene ID: ENSG00000153044
  
Biological name :CENPH
  
Synonyms : CENPH / centromere protein H / Q9H3R5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q13.2
Gene start: 69189548
Gene end: 69210357
  
Corresponding Affymetrix probe sets: 231772_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000283006
Ensembl peptide - ENSP00000426014
Ensembl peptide - ENSP00000423936
Ensembl peptide - ENSP00000422665
NCBI entrez gene - 64946     See in Manteia.
OMIM - 605607
RefSeq - NM_022909
RefSeq Peptide - NP_075060
swissprot - A0A0S2Z5T0
swissprot - D6RBJ6
swissprot - Q9H3R5
swissprot - H0Y9E6
swissprot - B3KVZ3
Ensembl - ENSG00000153044
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cenphENSDARG00000094892Danio rerio
 CENPHENSGALG00000014788Gallus gallus
 CenphENSMUSG00000045273Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008426  Centromere protein H


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0034080 CENP-A containing nucleosome assembly TAS
 biological_processGO:0051382 kinetochore assembly IEA
 biological_processGO:0051383 kinetochore organization TAS
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043515 kinetochore binding IDA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000123219 CENPK / Q9BS16 / centromere protein K  / complex
 ENSG00000102384 CENPI / Q92674 / centromere protein I  / complex






 

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