Manteia

ENSMUSG00000045273

Mus musculus

Features

Gene ID:	ENSMUSG00000045273

Biological name :	Cenph

Synonyms :	Cenph / Centromere protein H / Q9QYM8

Possible biological names infered from orthology :	Q9H3R5

Species:	Mus musculus

Chr. number:	13
Strand:	-1
Band:	D1
Gene start:	100759674
Gene end:	100775899

Corresponding Affymetrix probe sets:	10411728 (MoGene1.0st) 1422016_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000074988 NCBI entrez gene - 26886 See in Manteia. MGI - MGI:1349448 RefSeq - XM_011244667 RefSeq - NM_021886 RefSeq - XM_006517676 RefSeq - XM_006517678 RefSeq Peptide - NP_068686 swissprot - Q9QYM8 Ensembl - ENSMUSG00000045273

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR008426	Centromere protein H

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000278	mitotic cell cycle	ISO
biological_process	GO:0007059	chromosome segregation	ISO
biological_process	GO:0051382	kinetochore assembly	IEA
biological_process	GO:0051383	kinetochore organization	TAS
cellular_component	GO:0000775	chromosome, centromeric region	IEA
cellular_component	GO:0000776	kinetochore	ISO
cellular_component	GO:0000777	condensed chromosome kinetochore	IEA
cellular_component	GO:0005634	nucleus	ISO
cellular_component	GO:0005694	chromosome	IEA
cellular_component	GO:0005730	nucleolus	IEA
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0043515	kinetochore binding	IEA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001303	abnormal lens morphology	"malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Cbx2^{tm1b(KOMP)Wtsi}/Cbx2⁺ Genetic Background: C57BL/6N-Cbx2^{tm1b(KOMP)Wtsi}/H
MP:0001325	abnormal retina morphology	"structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cbx2^{tm1b(KOMP)Wtsi}/Cbx2⁺ Genetic Background: C57BL/6N-Cbx2^{tm1b(KOMP)Wtsi}/H
MP:0010025	decreased total body fat amount	"less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cbx2^{tm1b(KOMP)Wtsi}/Cbx2⁺ Genetic Background: C57BL/6N-Cbx2^{tm1b(KOMP)Wtsi}/H
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Cbx2^{tm1b(KOMP)Wtsi}/Cbx2⁺ Genetic Background: C57BL/6N-Cbx2^{tm1b(KOMP)Wtsi}/H

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000031262	Cenpi / Q8K1K4 / Centromere protein I / Q92674*	/ complex
ENSMUSG00000021714	Cenpk / Q9ESN5 / Centromere protein K / Q9BS16*	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr