ENSDARG00000094892


Danio rerio

Features
Gene ID: ENSDARG00000094892
  
Biological name :cenph
  
Synonyms : cenph / centromere protein H
  
Possible biological names infered from orthology : Q9H3R5 / Q9QYM8
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 17167876
Gene end: 17173694
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000157069
Ensembl peptide - ENSDARP00000123314
NCBI entrez gene - 567359     See in Manteia.
RefSeq - NM_001113609
RefSeq - XM_005166882
RefSeq Peptide - NP_001107081
swissprot - A8WHV8
ZFIN ID - ZDB-GENE-081104-340
Ensembl - ENSDARG00000094892
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CENPHENSGALG00000014788Gallus gallus
 CENPHENSG00000153044Homo sapiens
 CenphENSMUSG00000045273Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008426  Centromere protein H


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007052 mitotic spindle organization IMP
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0051382 kinetochore assembly IEA
 biological_processGO:2000117 negative regulation of cysteine-type endopeptidase activity IMP
 cellular_componentGO:0000776 kinetochore IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic , abnormal
brain neoplastic, invasive , abnormal
Show

 ZFA:0000012 central nervous system central nervous system chromatin condensed , abnormal
Show

 ZFA:0000035 lens lens neoplastic, invasive , abnormal
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 ZFA:0000075 spinal cord spinal cord apoptotic , abnormal
spinal cord opaque , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000123 liver liver neoplastic, invasive , abnormal
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 ZFA:0000152 retina retina neoplastic, invasive , abnormal
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 ZFA:0000204 esophagus esophagus neoplastic, invasive , abnormal
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 ZFA:0000368 integument integument rough , abnormal
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 ZFA:0001114 head head low brightness , abnormal
head apoptotic , abnormal
head opaque , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
trunk curved dorsal , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052565 cenpi / centromere protein I / Q8K1K4* / Q92674*  / complex






 

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contact: otassy@igbmc.fr