ENSG00000123843


Homo sapiens

Features
Gene ID: ENSG00000123843
  
Biological name :C4BPB
  
Synonyms : C4BPB / complement component 4 binding protein beta / P20851
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q32.1
Gene start: 207088842
Gene end: 207099993
  
Corresponding Affymetrix probe sets: 208209_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356045
Ensembl peptide - ENSP00000243611
Ensembl peptide - ENSP00000356043
Ensembl peptide - ENSP00000375790
Ensembl peptide - ENSP00000392237
NCBI entrez gene - 725     See in Manteia.
OMIM - 120831
RefSeq - XM_005273254
RefSeq - NM_000716
RefSeq - NM_001017364
RefSeq - NM_001017365
RefSeq - NM_001017366
RefSeq - NM_001017367
RefSeq Peptide - NP_001017367
RefSeq Peptide - NP_001017365
RefSeq Peptide - NP_001017366
RefSeq Peptide - NP_001017364
RefSeq Peptide - NP_000707
swissprot - Q5VVQ7
swissprot - P20851
Ensembl - ENSG00000123843
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CFB / P00751 / complement factor BENSG0000024364929
AL645922.1ENSG0000024425529
C2 / P06681 / complement C2ENSG0000016627824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006958 complement activation, classical pathway IEA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0030449 regulation of complement activation TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IDA
 biological_processGO:0045959 negative regulation of complement activation, classical pathway IDA
 biological_processGO:1903027 regulation of opsonization IC
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0044216 other organism cell IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000184500 PROS1 / P07225 / protein S  / reaction / complex
 ENSG00000224389 C4B / P0C0L5 / complement C4B (Chido blood group)  / reaction / complex
 ENSG00000244731 C4A / P0C0L4 / complement C4A (Rodgers blood group)  / reaction / complex
 ENSG00000166278 C2 / P06681 / complement C2  / complex
 ENSG00000123838 C4BPA / P04003 / complement component 4 binding protein alpha  / complex
 ENSG00000205403 CFI / P05156 / complement factor I  / reaction / complex






 

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