ENSG00000124225


Homo sapiens

Features
Gene ID: ENSG00000124225
  
Biological name :PMEPA1
  
Synonyms : PMEPA1 / prostate transmembrane protein, androgen induced 1 / Q969W9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.31
Gene start: 57648392
Gene end: 57711536
  
Corresponding Affymetrix probe sets: 217875_s_at (Human Genome U133 Plus 2.0 Array)   222449_at (Human Genome U133 Plus 2.0 Array)   222450_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379161
Ensembl peptide - ENSP00000379159
Ensembl peptide - ENSP00000379164
Ensembl peptide - ENSP00000401506
Ensembl peptide - ENSP00000265626
Ensembl peptide - ENSP00000344014
Ensembl peptide - ENSP00000345826
NCBI entrez gene - 56937     See in Manteia.
OMIM - 606564
RefSeq - NM_001255976
RefSeq - NM_020182
RefSeq - NM_199169
RefSeq - NM_199170
RefSeq - NM_199171
RefSeq Peptide - NP_954640
RefSeq Peptide - NP_001242905
RefSeq Peptide - NP_064567
RefSeq Peptide - NP_954638
RefSeq Peptide - NP_954639
swissprot - Q969W9
swissprot - A2A2F5
swissprot - A2A2F4
swissprot - Q5JY37
Ensembl - ENSG00000124225
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Pmepa1ENSMUSG00000038400Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15165 / LDLRAD4 / low density lipoprotein receptor class A domain containing 4ENSG0000016867560


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0010991 negative regulation of SMAD protein complex assembly IDA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0030521 androgen receptor signaling pathway NAS
 biological_processGO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0031901 early endosome membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0050699 WW domain binding IPI
 molecular_functionGO:0070412 R-SMAD binding IPI


Pathways (from Reactome)
Pathway description
Downregulation of TGF-beta receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000175387 SMAD2 / Q15796 / SMAD family member 2  / reaction / complex
 ENSG00000166949 SMAD3 / P84022 / SMAD family member 3  / reaction / complex






 

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