ENSG00000168675


Homo sapiens

Features
Gene ID: ENSG00000168675
  
Biological name :LDLRAD4
  
Synonyms : LDLRAD4 / low density lipoprotein receptor class A domain containing 4 / O15165
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: p11.21
Gene start: 13217498
Gene end: 13652755
  
Corresponding Affymetrix probe sets: 207996_s_at (Human Genome U133 Plus 2.0 Array)   209573_s_at (Human Genome U133 Plus 2.0 Array)   209574_s_at (Human Genome U133 Plus 2.0 Array)   233138_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000474783
Ensembl peptide - ENSP00000466771
Ensembl peptide - ENSP00000466772
Ensembl peptide - ENSP00000352420
Ensembl peptide - ENSP00000382741
Ensembl peptide - ENSP00000465244
Ensembl peptide - ENSP00000465573
Ensembl peptide - ENSP00000466178
Ensembl peptide - ENSP00000466490
NCBI entrez gene - 753     See in Manteia.
OMIM - 606571
RefSeq - XM_017025972
RefSeq - XM_017025962
RefSeq - XM_017025963
RefSeq - XM_017025964
RefSeq - XM_017025965
RefSeq - XM_017025966
RefSeq - XM_017025967
RefSeq - XM_017025968
RefSeq - XM_017025969
RefSeq - XM_017025970
RefSeq - XM_017025971
RefSeq - NM_001003674
RefSeq - NM_001003675
RefSeq - NM_001276249
RefSeq - NM_001276251
RefSeq - NM_181481
RefSeq - NM_181482
RefSeq - XM_005258140
RefSeq - XM_006722353
RefSeq - XM_006722354
RefSeq - XM_011525737
RefSeq - XM_011525738
RefSeq - XM_017025961
RefSeq Peptide - NP_001003675
RefSeq Peptide - NP_001263180
RefSeq Peptide - NP_852146
RefSeq Peptide - NP_852147
RefSeq Peptide - NP_001003674
RefSeq Peptide - NP_001263178
swissprot - K7EMG1
swissprot - K7EKD6
swissprot - O15165
swissprot - K7EJM9
Ensembl - ENSG00000168675
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ldlrad4aENSDARG00000070555Danio rerio
 ldlrad4bENSDARG00000054941Danio rerio
 LDLRAD4ENSGALG00000013886Gallus gallus
 Q8BWJ4ENSMUSG00000024544Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PMEPA1 / Q969W9 / prostate transmembrane protein, androgen induced 1ENSG0000012422556


Protein motifs (from Interpro)
Interpro ID Name
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR036055  LDL receptor-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0010719 negative regulation of epithelial to mesenchymal transition IMP
 biological_processGO:0010991 negative regulation of SMAD protein complex assembly IDA
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation IMP
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0070412 R-SMAD binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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