ENSG00000124535


Homo sapiens

Features
Gene ID: ENSG00000124535
  
Biological name :WRNIP1
  
Synonyms : Q96S55 / Werner helicase interacting protein 1 / WRNIP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p25.2
Gene start: 2765414
Gene end: 2786952
  
Corresponding Affymetrix probe sets: 218015_s_at (Human Genome U133 Plus 2.0 Array)   222489_s_at (Human Genome U133 Plus 2.0 Array)   227619_at (Human Genome U133 Plus 2.0 Array)   230847_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370150
Ensembl peptide - ENSP00000477551
Ensembl peptide - ENSP00000370141
Ensembl peptide - ENSP00000370146
Ensembl peptide - ENSP00000370148
NCBI entrez gene - 56897     See in Manteia.
OMIM - 608196
RefSeq - NM_020135
RefSeq - NM_130395
RefSeq Peptide - NP_064520
RefSeq Peptide - NP_569079
swissprot - Q96S55
Ensembl - ENSG00000124535
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wrnip1ENSDARG00000005218Danio rerio
 WRNIP1ENSGALG00000012856Gallus gallus
 Q91XU0ENSMUSG00000021400Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR006642  Zinc finger, Rad18-type putative
 IPR008921  DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
 IPR021886  MgsA AAA+ ATPase C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032423  AAA C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000731 DNA synthesis involved in DNA repair IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0030174 regulation of DNA-dependent DNA replication initiation IDA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IMP
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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