ENSMUSG00000021400


Mus musculus

Features
Gene ID: ENSMUSG00000021400
  
Biological name :Wrnip1
  
Synonyms : Q91XU0 / Werner helicase interacting protein 1 / Wrnip1
  
Possible biological names infered from orthology : Q96S55
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A3.2
Gene start: 32802038
Gene end: 32822609
  
Corresponding Affymetrix probe sets: 10404412 (MoGene1.0st)   1429638_at (Mouse Genome 430 2.0 Array)   1448376_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021832
Ensembl peptide - ENSMUSP00000154988
NCBI entrez gene - 78903     See in Manteia.
MGI - MGI:1926153
RefSeq - NM_030215
RefSeq Peptide - NP_084491
swissprot - Q91XU0
Ensembl - ENSMUSG00000021400
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wrnip1ENSDARG00000005218Danio rerio
 WRNIP1ENSGALG00000012856Gallus gallus
 Q96S55ENSG00000124535Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR006642  Zinc finger, Rad18-type putative
 IPR008921  DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
 IPR021886  MgsA AAA+ ATPase C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032423  AAA C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000731 DNA synthesis involved in DNA repair IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0030174 regulation of DNA-dependent DNA replication initiation IEA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity ISO
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wbp2tm2a(EUCOMM)Wtsi/Wbp2tm2a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Wbp2tm2a(EUCOMM)Wtsi/Cnrm

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wbp2tm2a(EUCOMM)Wtsi/Wbp2tm2a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Wbp2tm2a(EUCOMM)Wtsi/Cnrm

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Wbp2tm2a(EUCOMM)Wtsi/Wbp2tm2a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Wbp2tm2a(EUCOMM)Wtsi/Cnrm

 MP:0005316 abnormal response to tactile stimuli "anomalous reflex action normally induced by touch or pain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wbp2tm2a(EUCOMM)Wtsi/Wbp2tm2a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Wbp2tm2a(EUCOMM)Wtsi/Cnrm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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