ENSG00000125458


Homo sapiens

Features
Gene ID: ENSG00000125458
  
Biological name :NT5C
  
Synonyms : 5, 3-nucleotidase, cytosolic / NT5C / Q8TCD5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 75130225
Gene end: 75131795
  
Corresponding Affymetrix probe sets: 1557303_at (Human Genome U133 Plus 2.0 Array)   219214_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000462123
Ensembl peptide - ENSP00000462712
Ensembl peptide - ENSP00000462981
Ensembl peptide - ENSP00000463947
Ensembl peptide - ENSP00000245552
Ensembl peptide - ENSP00000461927
Ensembl peptide - ENSP00000462455
Ensembl peptide - ENSP00000462697
NCBI entrez gene - 30833     See in Manteia.
OMIM - 191720
RefSeq - NM_001252377
RefSeq - NM_014595
RefSeq Peptide - NP_001239306
RefSeq Peptide - NP_055410
swissprot - V9HWF3
swissprot - J3KRC4
swissprot - J3KSF0
swissprot - J3KSX6
swissprot - J3KSY6
swissprot - J3QQX8
swissprot - Q8TCD5
Ensembl - ENSG00000125458
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Nt5cENSMUSG00000020736Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NT5M / Q9NPB1 / 5,3-nucleotidase, mitochondrialENSG0000020530959


Protein motifs (from Interpro)
Interpro ID Name
 IPR010708  5"(3")-deoxyribonucleotidase
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006195 purine nucleotide catabolic process TAS
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0009223 pyrimidine deoxyribonucleotide catabolic process IDA
 biological_processGO:0009264 deoxyribonucleotide catabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0046135 pyrimidine nucleoside catabolic process TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0008252 nucleotidase activity IDA
 molecular_functionGO:0008253 5"-nucleotidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019103 pyrimidine nucleotide binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Pyrimidine catabolism
Purine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125458 NT5C / Q8TCD5 / 5, 3-nucleotidase, cytosolic  / complex






 

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