ENSG00000125637


Homo sapiens

Features
Gene ID: ENSG00000125637
  
Biological name :PSD4
  
Synonyms : pleckstrin and Sec7 domain containing 4 / PSD4 / Q8NDX1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q14.1
Gene start: 113157325
Gene end: 113209396
  
Corresponding Affymetrix probe sets: 203317_at (Human Genome U133 Plus 2.0 Array)   215923_s_at (Human Genome U133 Plus 2.0 Array)   236616_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413997
Ensembl peptide - ENSP00000245796
Ensembl peptide - ENSP00000386373
Ensembl peptide - ENSP00000386606
NCBI entrez gene - 23550     See in Manteia.
OMIM - 614442
RefSeq - XM_006712394
RefSeq - NM_012455
RefSeq - XM_005263634
RefSeq - XM_006712392
RefSeq - XM_006712393
RefSeq Peptide - NP_036587
swissprot - H7BZ06
swissprot - B8ZZZ5
swissprot - Q8NDX1
Ensembl - ENSG00000125637
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Psd4ENSMUSG00000026979Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PSD / A5PKW4 / pleckstrin and Sec7 domain containingENSG0000005991531
PSD3 / Q9NYI0 / pleckstrin and Sec7 domain containing 3ENSG0000015601130
PSD2 / Q9BQI7 / pleckstrin and Sec7 domain containing 2ENSG0000014600527
GBF1 / Q92538 / golgi brefeldin A resistant guanine nucleotide exchange factor 1ENSG0000010786218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000904  Sec7 domain
 IPR001605  Pleckstrin homology domain, spectrin-type
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR023394  Sec7, C-terminal domain superfamily
 IPR035999  Sec7 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032012 regulation of ARF protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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