ENSG00000125812


Homo sapiens

Features
Gene ID: ENSG00000125812
  
Biological name :GZF1
  
Synonyms : GDNF inducible zinc finger protein 1 / GZF1 / Q9H116
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p11.21
Gene start: 23362182
Gene end: 23373063
  
Corresponding Affymetrix probe sets: 225884_s_at (Human Genome U133 Plus 2.0 Array)   234055_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000338290
Ensembl peptide - ENSP00000366250
Ensembl peptide - ENSP00000410009
NCBI entrez gene - 64412     See in Manteia.
OMIM - 613842
RefSeq - XM_017028019
RefSeq - NM_001317012
RefSeq - NM_001317019
RefSeq - NM_022482
RefSeq - XM_005260802
RefSeq - XM_011529321
RefSeq - XM_011529322
RefSeq - XM_017028017
RefSeq - XM_017028018
RefSeq - XM_005260800
RefSeq Peptide - NP_001303948
RefSeq Peptide - NP_071927
RefSeq Peptide - NP_001303941
swissprot - Q5JXG1
swissprot - Q9H116
Ensembl - ENSG00000125812
  
Related genetic diseases (OMIM): 617662 - Joint laxity, short stature, and myopia, 617662

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnrnpa0lENSDARG00000076380Danio rerio
 GZF1ENSGALG00000008350Gallus gallus
 Gzf1ENSMUSG00000027439Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding IMP
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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