ENSG00000125999


Homo sapiens

Features
Gene ID: ENSG00000125999
  
Biological name :BPIFB1
  
Synonyms : BPIFB1 / BPI fold containing family B member 1 / Q8TDL5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.21
Gene start: 33273480
Gene end: 33309878
  
Corresponding Affymetrix probe sets: 226067_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390471
Ensembl peptide - ENSP00000253354
NCBI entrez gene - 92747     See in Manteia.
RefSeq - NM_033197
RefSeq Peptide - NP_149974
swissprot - Q8TDL5
swissprot - A2A2R0
Ensembl - ENSG00000125999
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Bpifb1ENSMUSG00000027485Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BPIFA1 / Q9NP55 / BPI fold containing family A member 1ENSG0000019818311


Protein motifs (from Interpro)
Interpro ID Name
 IPR001124  Lipid-binding serum glycoprotein, C-terminal
 IPR017942  Lipid-binding serum glycoprotein, N-terminal
 IPR017943  Bactericidal permeability-increasing protein, alpha/beta domain superfamily
 IPR021193  BPI fold-containing family B member 1
 IPR032942  BPI/LBP/Plunc family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002227 innate immune response in mucosa IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0034144 negative regulation of toll-like receptor 4 signaling pathway IDA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr