ENSMUSG00000027485


Mus musculus

Features
Gene ID: ENSMUSG00000027485
  
Biological name :Bpifb1
  
Synonyms : Bpifb1 / BPI fold-containing family B member 1 / Q61114
  
Possible biological names infered from orthology : Q8TDL5
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 154190818
Gene end: 154220369
  
Corresponding Affymetrix probe sets: 10477495 (MoGene1.0st)   1423719_at (Mouse Genome 430 2.0 Array)   1439423_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028987
Ensembl peptide - ENSMUSP00000080501
NCBI entrez gene - 228801     See in Manteia.
MGI - MGI:2137431
RefSeq - NM_001012392
RefSeq - NM_153418
RefSeq Peptide - NP_001012392
RefSeq Peptide - NP_700467
swissprot - Q61114
Ensembl - ENSMUSG00000027485
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BPIFB1ENSG00000125999Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bpifa1 / P97361 / BPI fold-containing family A member 1 / Q9NP55*ENSMUSG0000002748312
Bpifa5 / Q9CQX3 / BPI fold-containing family A member 5 / BPIFA1* / Q9NP55* / BPI fold containing family A member 1*ENSMUSG0000002748412


Protein motifs (from Interpro)
Interpro ID Name
 IPR001124  Lipid-binding serum glycoprotein, C-terminal
 IPR017942  Lipid-binding serum glycoprotein, N-terminal
 IPR017943  Bactericidal permeability-increasing protein, alpha/beta domain superfamily
 IPR021193  BPI fold-containing family B member 1
 IPR032942  BPI/LBP/Plunc family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002227 innate immune response in mucosa ISO
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0034144 negative regulation of toll-like receptor 4 signaling pathway ISO
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

 MP:0001102 small superior vagus ganglion "reduced size of the upper ganglion of the vagus nerve located at the jugular foramen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
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Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

 MP:0002133 abnormal respiratory system physiology "anomalous function of the pulmonary system; inability or reduced ability to intake and exchange oxygen and carbon dioxide with the environment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gpc6tm1Lex/Gpc6tm1Lex,Ihhtm1Amc/Ihhtm1Amc
Genetic Background: involves: 129S1/Sv * 129S5/SvEvBrd * 129X1/SvJ * C57BL/6N

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gpc6tm1Lex/Gpc6tm1Lex,Ihhtm1Amc/Ihhtm1Amc
Genetic Background: involves: 129S1/Sv * 129S5/SvEvBrd * 129X1/SvJ * C57BL/6N

 MP:0009709 hydrometra "an accumulation in the uterine lumen of normal secretions that ordinarily drain from the body but are retained when the cervix or vagina is significantly or completely closed" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Aspatm1b(EUCOMM)Wtsi/Aspatm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Aspatm1b(EUCOMM)Wtsi/Ieg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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