ENSG00000126709


Homo sapiens

Features
Gene ID: ENSG00000126709
  
Biological name :IFI6
  
Synonyms : IFI6 / interferon alpha inducible protein 6 / P09912
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.3
Gene start: 27666061
Gene end: 27672218
  
Corresponding Affymetrix probe sets: 204415_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000342513
Ensembl peptide - ENSP00000354736
Ensembl peptide - ENSP00000355152
NCBI entrez gene - 2537     See in Manteia.
OMIM - 147572
RefSeq - NM_022872
RefSeq - NM_002038
RefSeq - NM_022873
RefSeq Peptide - NP_002029
RefSeq Peptide - NP_075010
RefSeq Peptide - NP_075011
swissprot - P09912
Ensembl - ENSG00000126709
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-188i13.10ENSDARG00000075151Danio rerio
 si:dkey-188i13.11ENSDARG00000092895Danio rerio
 si:dkey-188i13.6ENSDARG00000074217Danio rerio
 si:dkey-188i13.9ENSDARG00000074754Danio rerio
 zgc:152791ENSDARG00000039243Danio rerio
 IFI27L2ENSGALG00000021627Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H2X8 / IFI27L2 / interferon alpha inducible protein 27 like 2ENSG0000011963234
Q96BM0 / IFI27L1 / interferon alpha inducible protein 27 like 1ENSG0000016594833
IFI27 / interferon alpha inducible protein 27ENSG0000016594931


Protein motifs (from Interpro)
Interpro ID Name
 IPR009311  Interferon alpha-inducible protein IFI6/IFI27-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001836 release of cytochrome c from mitochondria IMP
 biological_processGO:0006955 immune response TAS
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0051902 negative regulation of mitochondrial depolarization IMP
 biological_processGO:0060337 type I interferon signaling pathway TAS
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IMP
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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