ENSG00000127125


Homo sapiens

Features
Gene ID: ENSG00000127125
  
Biological name :PPCS
  
Synonyms : phosphopantothenoylcysteine synthetase / PPCS / Q9HAB8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.2
Gene start: 42456117
Gene end: 42473385
  
Corresponding Affymetrix probe sets: 218341_at (Human Genome U133 Plus 2.0 Array)   230897_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361637
Ensembl peptide - ENSP00000361641
Ensembl peptide - ENSP00000361642
Ensembl peptide - ENSP00000361643
NCBI entrez gene - 79717     See in Manteia.
OMIM - 609853
RefSeq - NM_024664
RefSeq - NM_001287511
RefSeq - NM_001077447
RefSeq - NM_001287506
RefSeq - NM_001287508
RefSeq - NM_001287509
RefSeq - NM_001287510
RefSeq Peptide - NP_001070915
RefSeq Peptide - NP_001274435
RefSeq Peptide - NP_001274437
RefSeq Peptide - NP_001274438
RefSeq Peptide - NP_001274439
RefSeq Peptide - NP_001274440
RefSeq Peptide - NP_078940
swissprot - Q5VVM2
swissprot - Q5VVM3
swissprot - Q9HAB8
Ensembl - ENSG00000127125
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppcsENSDARG00000061889Danio rerio
 PPCSENSGALG00000004882Gallus gallus
 PpcsENSMUSG00000028636Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007085  DNA/pantothenate metabolism flavoprotein, C-terminal
 IPR035929  CoaB-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009108 coenzyme biosynthetic process TAS
 biological_processGO:0015937 coenzyme A biosynthetic process IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004632 phosphopantothenate--cysteine ligase activity TAS
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Coenzyme A biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000127125 PPCS / Q9HAB8 / phosphopantothenoylcysteine synthetase  / complex






 

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contact: otassy@igbmc.fr