ENSG00000127452


Homo sapiens

Features
Gene ID: ENSG00000127452
  
Biological name :FBXL12
  
Synonyms : F-box and leucine rich repeat protein 12 / FBXL12 / Q9NXK8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 9810267
Gene end: 9827816
  
Corresponding Affymetrix probe sets: 220127_s_at (Human Genome U133 Plus 2.0 Array)   237256_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468766
Ensembl peptide - ENSP00000468033
Ensembl peptide - ENSP00000468369
Ensembl peptide - ENSP00000247977
Ensembl peptide - ENSP00000464784
Ensembl peptide - ENSP00000464858
Ensembl peptide - ENSP00000465439
Ensembl peptide - ENSP00000466142
Ensembl peptide - ENSP00000467059
Ensembl peptide - ENSP00000467359
Ensembl peptide - ENSP00000467467
Ensembl peptide - ENSP00000467523
Ensembl peptide - ENSP00000467859
NCBI entrez gene - 54850     See in Manteia.
OMIM - 609079
RefSeq - NM_001316937
RefSeq - NM_017703
RefSeq - NM_001316942
RefSeq - NM_001316941
RefSeq - NM_001316940
RefSeq - NM_001316939
RefSeq - NM_001316938
RefSeq - NM_001316936
RefSeq Peptide - NP_001303868
RefSeq Peptide - NP_001303865
RefSeq Peptide - NP_001303866
RefSeq Peptide - NP_001303867
RefSeq Peptide - NP_001303869
RefSeq Peptide - NP_001303870
RefSeq Peptide - NP_001303871
RefSeq Peptide - NP_060173
swissprot - K7EIR3
swissprot - Q9NXK8
swissprot - K7EIK3
swissprot - K7ESL6
swissprot - K7EQY7
swissprot - K7EQJ7
swissprot - K7EPT3
swissprot - K7EPN7
swissprot - K7ELM5
swissprot - K7EK37
Ensembl - ENSG00000127452
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Fbxl12ENSMUSG00000066892Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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