ENSG00000127481


Homo sapiens

Features
Gene ID: ENSG00000127481
  
Biological name :UBR4
  
Synonyms : Q5T4S7 / ubiquitin protein ligase E3 component n-recognin 4 / UBR4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.13
Gene start: 19074506
Gene end: 19210276
  
Corresponding Affymetrix probe sets: 1563113_at (Human Genome U133 Plus 2.0 Array)   211950_at (Human Genome U133 Plus 2.0 Array)   215636_at (Human Genome U133 Plus 2.0 Array)   231889_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395313
Ensembl peptide - ENSP00000364403
Ensembl peptide - ENSP00000404897
Ensembl peptide - ENSP00000364366
Ensembl peptide - ENSP00000364372
Ensembl peptide - ENSP00000364373
NCBI entrez gene - 23352     See in Manteia.
OMIM - 609890
RefSeq - XM_017000830
RefSeq - NM_020765
RefSeq - XM_017000824
RefSeq - XM_017000825
RefSeq - XM_017000826
RefSeq - XM_017000827
RefSeq - XM_017000828
RefSeq - XM_017000829
RefSeq - XM_011541108
RefSeq - XM_011541109
RefSeq - XM_011541110
RefSeq - XM_011541111
RefSeq - XM_011541112
RefSeq - XM_011541113
RefSeq - XM_011541114
RefSeq - XM_011541115
RefSeq - XM_011541116
RefSeq - XM_011541117
RefSeq - XM_011541118
RefSeq - XM_011541119
RefSeq - XM_011541120
RefSeq - XM_011541121
RefSeq - XM_017000822
RefSeq - XM_017000823
RefSeq Peptide - NP_065816
swissprot - Q5T4S7
swissprot - Q5TBN9
swissprot - X6R960
swissprot - X6RE05
swissprot - A0A0A0MSW0
Ensembl - ENSG00000127481
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ubr4ENSDARG00000009549Danio rerio
 UBR4ENSGALG00000030563Gallus gallus
 Ubr4ENSMUSG00000066036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003126  Zinc finger, UBR-type
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR025704  E3 ubiquitin ligase, UBR4
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070821 tertiary granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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