ENSG00000127588


Homo sapiens

Features
Gene ID: ENSG00000127588
  
Biological name :GNG13
  
Synonyms : GNG13 / G protein subunit gamma 13 / Q9P2W3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 798041
Gene end: 800733
  
Corresponding Affymetrix probe sets: 220806_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000248150
NCBI entrez gene - 51764     See in Manteia.
OMIM - 607298
RefSeq - NM_016541
RefSeq Peptide - NP_057625
swissprot - Q9P2W3
Ensembl - ENSG00000127588
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gng13bENSDARG00000037921Danio rerio
 GNG13ENSGALG00000005293Gallus gallus
 Gng13ENSMUSG00000025739Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001770  G-protein, gamma subunit
 IPR015898  G-protein gamma-like domain
 IPR036284  G-protein gamma-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0071377 cellular response to glucagon stimulus TAS
 cellular_componentGO:0005834 heterotrimeric G-protein complex IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030425 dendrite IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0031681 G-protein beta-subunit binding IPI


Pathways (from Reactome)
Pathway description
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000111664 GNB3 / P16520 / G protein subunit beta 3  / complex
 ENSG00000214415 GNAT3 / A8MTJ3 / G protein subunit alpha transducin 3  / complex






 

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