ENSG00000128040


Homo sapiens

Features
Gene ID: ENSG00000128040
  
Biological name :SPINK2
  
Synonyms : P20155 / serine peptidase inhibitor, Kazal type 2 / SPINK2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q12
Gene start: 56809860
Gene end: 56821742
  
Corresponding Affymetrix probe sets: 206310_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423858
Ensembl peptide - ENSP00000425961
Ensembl peptide - ENSP00000248701
Ensembl peptide - ENSP00000487028
Ensembl peptide - ENSP00000478284
Ensembl peptide - ENSP00000477722
NCBI entrez gene - 6691     See in Manteia.
OMIM - 605753
RefSeq - XM_011534405
RefSeq - NM_001271718
RefSeq - NM_001271719
RefSeq - NM_001271720
RefSeq - NM_001271721
RefSeq - NM_001271722
RefSeq - NM_021114
RefSeq Peptide - NP_001258649
RefSeq Peptide - NP_001258651
RefSeq Peptide - NP_066937
RefSeq Peptide - NP_001258647
RefSeq Peptide - NP_001258648
RefSeq Peptide - NP_001258650
swissprot - A0A087WTA9
swissprot - D6RI10
swissprot - D6RC51
swissprot - A0A0D9SFZ8
swissprot - P20155
swissprot - A0A024RD95
swissprot - A0A087WU11
Ensembl - ENSG00000128040
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-203a12.3ENSDARG00000099689Danio rerio
 si:dkey-203a12.6ENSDARG00000100051Danio rerio
 si:dkey-203a12.8ENSDARG00000101290Danio rerio
 si:dkey-77g12.1ENSDARG00000103833Danio rerio
 si:dkey-77g12.4ENSDARG00000103336Danio rerio
 SPINK2ENSDARG00000102868Danio rerio
 zgc:158852ENSDARG00000102076Danio rerio
 Q8BMY7ENSMUSG00000053030Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002350  Kazal domain
 IPR036058  Kazal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0060046 regulation of acrosome reaction IBA
 biological_processGO:1900004 negative regulation of serine-type endopeptidase activity IBA
 cellular_componentGO:0001669 acrosomal vesicle IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004866 endopeptidase inhibitor activity TAS
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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