ENSG00000128294


Homo sapiens

Features
Gene ID: ENSG00000128294
  
Biological name :TPST2
  
Synonyms : O60704 / TPST2 / tyrosylprotein sulfotransferase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.1
Gene start: 26521983
Gene end: 26596717
  
Corresponding Affymetrix probe sets: 204079_at (Human Genome U133 Plus 2.0 Array)   229449_at (Human Genome U133 Plus 2.0 Array)   235761_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000339813
Ensembl peptide - ENSP00000381180
Ensembl peptide - ENSP00000416791
Ensembl peptide - ENSP00000414809
Ensembl peptide - ENSP00000403875
Ensembl peptide - ENSP00000403758
Ensembl peptide - ENSP00000401134
Ensembl peptide - ENSP00000400357
Ensembl peptide - ENSP00000385192
NCBI entrez gene - 8459     See in Manteia.
OMIM - 603126
RefSeq - NM_003595
RefSeq - NM_001008566
RefSeq - XM_006724338
RefSeq Peptide - NP_001008566
RefSeq Peptide - NP_003586
swissprot - B1AHJ5
swissprot - B1AHK0
swissprot - O60704
swissprot - A0A024R1G9
swissprot - B1AHJ9
swissprot - B1AHJ8
swissprot - B1AHJ7
swissprot - B1AHJ6
Ensembl - ENSG00000128294
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tpst2ENSDARG00000099155Danio rerio
 TPST2ENSGALG00000005626Gallus gallus
 Tpst2ENSMUSG00000029344Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TPST1 / O60507 / tyrosylprotein sulfotransferase 1ENSG0000016990264


Protein motifs (from Interpro)
Interpro ID Name
 IPR026634  Protein-tyrosine sulfotransferase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006478 peptidyl-tyrosine sulfation IEA
 biological_processGO:0050427 3"-phosphoadenosine 5"-phosphosulfate metabolic process TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008476 protein-tyrosine sulfotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Cytosolic sulfonation of small molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114631 PODXL2 / Q9NZ53 / podocalyxin like 2  / reaction






 

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