ENSG00000128951


Homo sapiens

Features
Gene ID: ENSG00000128951
  
Biological name :DUT
  
Synonyms : deoxyuridine triphosphatase / DUT / P33316
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q21.1
Gene start: 48331011
Gene end: 48343373
  
Corresponding Affymetrix probe sets: 208955_at (Human Genome U133 Plus 2.0 Array)   208956_x_at (Human Genome U133 Plus 2.0 Array)   209932_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454041
Ensembl peptide - ENSP00000453717
Ensembl peptide - ENSP00000454183
Ensembl peptide - ENSP00000370376
Ensembl peptide - ENSP00000405160
Ensembl peptide - ENSP00000452749
Ensembl peptide - ENSP00000452814
Ensembl peptide - ENSP00000453667
Ensembl peptide - ENSP00000453683
NCBI entrez gene - 1854     See in Manteia.
OMIM - 601266
RefSeq - XM_011521315
RefSeq - NM_001025248
RefSeq - NM_001025249
RefSeq - NM_001948
RefSeq Peptide - NP_001317215
RefSeq Peptide - NP_001939
RefSeq Peptide - NP_001020419
RefSeq Peptide - NP_001020420
swissprot - A0A0C4DGL3
swissprot - H0YKC5
swissprot - H0YKI0
swissprot - H0YMP1
swissprot - H0YMM5
swissprot - H0YNJ9
swissprot - H0YNW5
swissprot - P33316
Ensembl - ENSG00000128951
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DUTENSDARG00000106529Danio rerio
 DUTENSGALG00000038032Gallus gallus
 DutENSMUSG00000027203Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008181  Deoxyuridine triphosphate nucleotidohydrolase
 IPR029054  dUTPase-like
 IPR033704  dUTPase, trimeric
 IPR036157  dUTPase-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process TAS
 biological_processGO:0006226 dUMP biosynthetic process IEA
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0015949 nucleobase-containing small molecule interconversion TAS
 biological_processGO:0046080 dUTP metabolic process IEA
 biological_processGO:0046081 dUTP catabolic process IBA
 biological_processGO:2000272 negative regulation of signaling receptor activity IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000287 magnesium ion binding IBA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004170 dUTP diphosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000128951 DUT / P33316 / deoxyuridine triphosphatase  / complex






 

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contact: otassy@igbmc.fr