ENSG00000129009


Homo sapiens

Features
Gene ID: ENSG00000129009
  
Biological name :ISLR
  
Synonyms : immunoglobulin superfamily containing leucine rich repeat / ISLR / O14498
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q24.1
Gene start: 74173671
Gene end: 74176872
  
Corresponding Affymetrix probe sets: 207191_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453884
Ensembl peptide - ENSP00000249842
Ensembl peptide - ENSP00000378550
Ensembl peptide - ENSP00000453105
NCBI entrez gene - 3671     See in Manteia.
OMIM - 602059
RefSeq - NM_005545
RefSeq - NM_201526
RefSeq Peptide - NP_005536
RefSeq Peptide - NP_958934
swissprot - O14498
swissprot - A0A146E5L3
swissprot - H0YL90
swissprot - H0YN67
Ensembl - ENSG00000129009
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 islr2ENSDARG00000051875Danio rerio
 ENSGALG00000021525Gallus gallus
 ISLR2ENSGALG00000029151Gallus gallus
 IslrENSMUSG00000037206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ISLR2 / Q6UXK2 / immunoglobulin superfamily containing leucine rich repeat 2ENSG0000016717851
LRIT1 / Q9P2V4 / leucine rich repeat, Ig-like and transmembrane domains 1ENSG0000014860222
LRIT3 / Q3SXY7 / leucine rich repeat, Ig-like and transmembrane domains 3ENSG0000018342322
LRIT2 / A6NDA9 / leucine rich repeat, Ig-like and transmembrane domains 2ENSG0000020403320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007155 cell adhesion TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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