ENSG00000130303


Homo sapiens

Features
Gene ID: ENSG00000130303
  
Biological name :BST2
  
Synonyms : bone marrow stromal cell antigen 2 / BST2 / Q10589
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 17402939
Gene end: 17405648
  
Corresponding Affymetrix probe sets: 201641_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000252593
NCBI entrez gene - 684     See in Manteia.
OMIM - 600534
RefSeq - NM_004335
RefSeq Peptide - NP_004326
swissprot - A0A024R7H5
swissprot - Q10589
Ensembl - ENSG00000130303
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Bst2ENSMUSG00000046718Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024886  Bone marrow stromal antigen 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002737 negative regulation of plasmacytoid dendritic cell cytokine production IDA
 biological_processGO:0006959 humoral immune response TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISS
 biological_processGO:0034341 response to interferon-gamma ISS
 biological_processGO:0035455 response to interferon-alpha ISS
 biological_processGO:0035456 response to interferon-beta ISS
 biological_processGO:0042113 B cell activation IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling HMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045071 negative regulation of viral genome replication IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0060337 type I interferon signaling pathway TAS
 biological_processGO:1901253 negative regulation of intracellular transport of viral material IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005771 multivesicular body IMP
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004871 obsolete signal transducer activity HMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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