ENSMUSG00000046718


Mus musculus

Features
Gene ID: ENSMUSG00000046718
  
Biological name :Bst2
  
Synonyms : Bone marrow stromal antigen 2 / Bst2 / Q8R2Q8
  
Possible biological names infered from orthology : bone marrow stromal cell antigen 2 / Q10589
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.3
Gene start: 71534255
Gene end: 71537456
  
Corresponding Affymetrix probe sets: 10579532 (MoGene1.0st)   1424921_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000051921
NCBI entrez gene - 69550     See in Manteia.
MGI - MGI:1916800
RefSeq - NM_198095
RefSeq Peptide - NP_932763
swissprot - Q8R2Q8
Ensembl - ENSMUSG00000046718
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BST2ENSG00000130303Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024886  Bone marrow stromal antigen 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002737 negative regulation of plasmacytoid dendritic cell cytokine production ISS
 biological_processGO:0009615 response to virus IDA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030308 negative regulation of cell growth ISS
 biological_processGO:0030336 negative regulation of cell migration ISS
 biological_processGO:0032956 regulation of actin cytoskeleton organization ISS
 biological_processGO:0034341 response to interferon-gamma IDA
 biological_processGO:0035455 response to interferon-alpha IDA
 biological_processGO:0035456 response to interferon-beta IDA
 biological_processGO:0045071 negative regulation of viral genome replication IMP
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0051607 defense response to virus IBA
 biological_processGO:1901253 negative regulation of intracellular transport of viral material IMP
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0000702 enlarged lymph nodes "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0002418 increased susceptibility to viral infection "greater likelihood that an organism will develop ill effects from a viral infection or from components of or toxins produced by a virus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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