ENSG00000130368


Homo sapiens

Features
Gene ID: ENSG00000130368
  
Biological name :MAS1
  
Synonyms : MAS1 / MAS1 proto-oncogene, G protein-coupled receptor / P04201
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q25.3
Gene start: 159906690
Gene end: 159916530
  
Corresponding Affymetrix probe sets: 208210_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000252660
NCBI entrez gene - 4142     See in Manteia.
OMIM - 165180
RefSeq - NM_002377
RefSeq Peptide - NP_002368
swissprot - P04201
swissprot - W8W3P4
Ensembl - ENSG00000130368
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011622Gallus gallus
 Mas1ENSMUSG00000068037Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96LB1 / MRGPRX2 / MAS related GPR family member X2ENSG0000018369533
Q96LA9 / MRGPRX4 / MAS related GPR family member X4ENSG0000017981733
Q96LB2 / MRGPRX1 / MAS related GPR family member X1ENSG0000017025531
MAS1L / P35410 / MAS1 proto-oncogene like, G protein-coupled receptorENSG0000020468730
MRGPRD / Q8TDS7 / MAS related GPR family member DENSG0000017293830
Q96LB0 / MRGPRX3 / MAS related GPR family member X3ENSG0000017982630
MRGPRF / Q96AM1 / MAS related GPR family member FENSG0000017293527
MRGPRE / Q86SM8 / MAS related GPR family member EENSG0000018435024
MRGPRG / Q86SM5 / MAS related GPR family member GENSG0000018217022


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000820  Proto-oncogene Mas
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR026234  Mas-related G protein-coupled receptor family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0034698 response to gonadotropin IEA
 biological_processGO:0038166 angiotensin-activated signaling pathway IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0045740 positive regulation of DNA replication IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0060732 positive regulation of inositol phosphate biosynthetic process IEA
 biological_processGO:0070528 protein kinase C signaling IMP
 biological_processGO:0071375 cellular response to peptide hormone stimulus IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001595 angiotensin receptor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0004945 angiotensin type II receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017046 peptide hormone binding IEA
 molecular_functionGO:0042277 peptide binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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